Differentiation Inducing Compound Library

Cat. No. :	CS-L038	(1277 compounds)

Library Contents: PDF | SDF

Stem cells, which are found in all multi-cellular organisms, can divide and differentiate into diverse special cell types and can self-renew to produce more stem cells. To be useful in therapy, stem cells must be converted into desired cell types as necessary which is called induced differentiation or directed differentiation. Understanding and using signaling pathways for differentiation is an important method in successful regenerative medicine. Small molecules or growth factors induce the conversion of stem cells into appropriate progenitor cells, which will later give rise to the desired cell type. There is a variety of signal molecules and molecular families that may affect the establishment of germ layers in vivo, such as fibroblast growth factors (FGFs); the wnt family or superfamily of transforming growth factors β (TGFβ) and bone morphogenetic proteins (BMP). Unfortunately, for now, a high cost of recombinant factors is likely to limit their use on a larger scale in medicine. The more promising technique focuses on the use of small molecules. These small molecules can be used for either activating or deactivating specific signaling pathways. They enhance reprogramming efficiency by creating cells that are compatible with the desired type of tissue. It is a cheaper and non-immunogenic method.

MCE Differentiation Inducing Compound Library contains a unique collection of 1277 compounds that act on signaling pathways for differentiation. These compounds are potential stimulators for induced differentiation. This library is a useful tool for researching directed differentiation and regenerative medicine.

Size (Pre-dissolved DMSO or Solid)	Stock	Price
30 μL/well (10 mM solution)	In-stock	Get quote
50 μL/well (10 mM solution)	In-stock	Get quote
100 μL/well (10 mM solution)	In-stock	Get quote
250 μL/well (10 mM solution)	In-stock	Get quote

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Data Sheet
Description & Advantages
Composition
Contents

Formulation:	A collection of 1277 compounds supplied as pre-dissolved Solutions or Solid
Container:	96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:	-80°C
Shipping:	Blue ice