Ion Channel Compound Library

Cat. No. : CS-L166 (1043 compounds)
Library Contents: PDF | SDF

The ion channel is a membrane-binding enzyme whose catalytic site is an ion conduction pore, which is opened and closed in response to specific environmental stimuli (voltage, ligand concentration, membrane tension, temperature, etc.). The Ion channel provides pores for the passive diffusion of ions on the biofilm. They are usually highly selective to specific ionic species, resulting in classification as sodium (Na+), potassium (K+), calcium (Ca2+), chloride (Cl-) and unspecific cation channels. Ion channel is an important contributor to cell signal transduction and homeostasis. In addition to electrical signal transduction, Ion channel also has many functions: chemical signal (Ca2+ as the second messenger), trans-epithelial transport, regulation of cytoplasmic or vesicular ion concentration and pH, and regulation of cell volume. Therefore, Ion channel dysfunction can lead to many tissue diseases. The Ion channel provides pores for the passive diffusion of ions on the biofilm. Ion channel can usually be studied by electrophysiological techniques.

MCE designs a unique collection of 1043 small molecules related to ion channel. It is a good tool to be used for research on cardiovascular and other diseases.

Size (Pre-dissolved DMSO or Solid) Stock Price
30 μL/well (10 mM solution) In-stock Get quote
50 μL/well (10 mM solution) In-stock Get quote
100 μL/well (10 mM solution) In-stock Get quote
250 μL/well (10 mM solution) In-stock Get quote
Products are for research use only. Not for human use. We do not sell to patients.

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  • Data Sheet

  • Description & Advantages

  • Composition

  • Contents

Formulation:A collection of 1043 small molecules related to ion channel supplied as pre-dissolved Solutions or Solid
Container:96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:-80°C
Shipping:Blue ice or dry ice

•   A unique collection of 1043 small molecules related to ion channel for high throughput screening (HTS) and high content screening (HCS).

•   Targets such as Calcium Channel, Chloride Channel, iGluR, Potassium Channel and more.

•   Structurally diverse, medicinally active and cell permeable.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some compounds have been approved by FDA.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

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