Autoimmune Disease Compound Library

Cat. No. : CS-L156 (414 compounds)
Library Contents: PDF | SDF

Autoimmune disease is a pathological disease characterized by inflammatory disorders targeting autoantigens. The routine treatment of autoimmune diseases suppresses general immune function to regulate uncontrolled inflammation. The current targeted immunotherapy suppresses the main pro-inflammatory signaling pathways by blocking inflammatory cytokines, cell surface molecules, and intracellular kinases. As key participants in innate immunity, macrophages and dendritic cells (DCs) are crucial for Ag presentation and pro-inflammatory cytokine production, such as TNF and IL-1 β、 IL-6, IL-23, B cell activating factor (BAFF), and the proliferation-inducing ligand (APRIL, also known as TNFSF13A).

MCE designs a unique collection of 414 autoimmune disease-related compounds, covering multiple targets and subtypes, such as TNF Receptor, IFNAR, JAK, Btk, TLR, IL-6, IL-17, IL-23, etc. It is a useful tool for screening autoimmune disease drugs.

Size (Pre-dissolved DMSO or Solid) Stock Price
30 μL/well (10 mM solution) In-stock Get quote
50 μL/well (10 mM solution) In-stock Get quote
100 μL/well (10 mM solution) In-stock Get quote
250 μL/well (10 mM solution) In-stock Get quote
Products are for research use only. Not for human use. We do not sell to patients.

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  • Data Sheet

  • Description & Advantages

  • Composition

  • Contents

Formulation:A collection of 414 small molecules related to autoimmune diseases supplied as pre-dissolved Solutions or Solid
Container:96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode
Storage:-80°C
Shipping:Blue ice or dry ice

•   A unique collection of 414 small molecules related to autoimmune diseases for high throughput screening (HTS) and high content screening (HCS).

•   Targets such as TNF Receptor, IFNAR, JAK, Btk, TLR, and more.

•   A useful tool for drug discovery.

•   Target diverse, medicinally active and cell permeable.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

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    Autoimmune Disease Compound Library